Coagulation is a dynamic process and the understanding of the blood coagulation system has evolved over the recent years in anaesthetic practice. Vitamin k modifies certain proteins that are required for blood coagulation.
Which Vitamin Is Necessary For Blood Clotting Quora
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The modification of the proteins allows them to bind calcium ions.
What vitamin is mostly required for blood coagulation. This feature highlights in detail the biological roles food sources deficiency conditions and toxicity of this fat soluble vitamin. 1 blood coagulation 2 bone metabolism vitamin k is required for the process that adds calcium to some proteins post translational process also effect gene expression of some proteins and cells involved in bone metabolism vitamin k works through nuclear receptors. Vitamin k is needed for the post translational modification of certain proteins mostly required for blood coagulation.
Calcium is also required at other points in the coagulation cascade. Vitamin k is mostly required for blood coagulation but it is also involved in metabolic pathways in bone and other tissue. Vitamin k k comes from koagulations vitamin in the german and scandinavian languages denotes a group of lipophilic hydrophobic vitamins that are needed for the posttranslational modification of certain proteins mostly required for blood coagulation but also a number of other proteins that chelate calcium ion and are involved.
Although the traditional classification of the coagulation system into extrinsic and intrinsic pathway is still valid the newer insights into coagulation provide more authentic description of the same. Vitamin k is a fat soluble vitamin needed for a unique post translational chemical modification of proteins with calcium binding properties collectively known as vitamin k dependent proteins vkdps or gla proteins. Vitamin k2 23 epoxide is a vitamin k metabolite occurring in the ubiquinone secondary metabolite and other terpenoid quinone biosynthetic pathways.
Spinach avocados and milk are the best examples of vitamin k foods. The main vitamin k function is the synthesis of a protein essential for blood clotting. Vitamin k is an essential factor to a hepatic gamma glutamyl carboxylase that adds a carboxyl group to glutamic acid residues on factors ii vii ix and x as well as protein s protein c and protein z.
The human body requires vitamin k for complete synthesis of certain proteins that are needed for blood coagulation k from koagulation german for coagulation or for controlling binding of calcium in bones and other tissues. Vitamin k is a group of structurally similar fat soluble vitamins found in foods and in dietary supplements. Vitamin k is essential for blood clotting.
Vitamin k is necessary for the formation of prothrombin required for blood clotting while calcium can help in normalizing the clotting of blood. Proteins that act as clotting factors or coagulation factors are all made in the liver which requires vitamin k for this process.
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